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Note: All scientific statistics are interrelated with the notion of fold change. Thus, fold change is a quantitative metric of biological importance that is used to understand the outcome of an experiment. Understanding this relationship helps to explain why fold change is an important metric.
In this post, we talk about the concept of fold change, and its use as a quantitative metric to compare microarray experiment results. This post assumes that you have some basic understanding of the concept of fold change.
The graphical representation of fold change is a logarithmic ratio of the quantities of the target gene. It allows normalization for small variations in the amount of starting template, and allows comparisons of samples that have different starting amounts of the target mRNA.
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